“Tox” Neuromodulators

All About “Tox”

Unless you’ve been living under a rock, by now, you’ve probably heard about Botox®. Afterall, it is that *magic* injection that improves wrinkles, skin tone, and results in HAPPINESS (it’s true….Botox® has been shown to improve depressed mood)!

While most of us refer to all “Tox” brands as “Botox” this class of medications are formally referred to as neuromodulator agents and there are several brands available for use here in the USA. Those include Jeuveau®, Dysport®, Xeomin®, and good ‘ol Botox®. In fact, all of these medications contain the same active ingredient – Botulinium Type A. Tox products work by temporarily making it harder for you to make certain facial expressions, such as frowning, thus reducing lines created by the actions of these muscles. Side effects are minimal and include the potential for bruising and mild swelling at the injection sites and treatment effects are typically seen within a few days of injection.

For more information, including a comparison chart of the various brands, click here: Membership Benefits

At Tox & Tonic we specialize in Tox injections! Our Nurse Injectors have received extensive training in the use of Tox for both on-label and off-label (commonly treated but non-FDA approved) areas with ALL of the FDA-approved Tox products currently available. We understand the differences in effect between the various brands, as well as the effect of dosing changes, precise placement, and even specialty Tox treatments such as treatments for excessive sweating, MicroTox Tightening and HydraTox Gold Needling.

Nervous about getting Tox injections?! Don’t be! Our Nurse Injectors take your safety very seriously. All potential effects – both good and bad – will be discussed with you, in detail, prior to your treatment. We will make sure you feel comfortable with your treatment plan and that all of your questions are answered. We even offer a FREE VIRTUAL CONSULTATION so you can determine which treatment areas may be right for you!

We look forward to helping you ROCK YOUR TOX!

What’s The Difference Between The Various ‘Tox’ Brands?

While the active ingredient is the same throughout all of the products, the ‘recipe’ and manufacturing process varies amongst them. This variation can create subtle differences in duration, effect, and potency as shown in the chart, below.

Please note that not all Tox brands are available at every Tox & Tonic location.

Comparison Of Currently Available “TOX” Brands

Trade Name	JEUVEAU®	BOTOX®
Distributor	Evolus	Allergan
Scientific Name	PrabotulinumtoxinA	OnabotulinumtoxinA
Year FDA Approved	2019	2002
Standard Price/Unit	$12/unit	$14/unit
Member Price	$6.99/unit	$10.50/unit
Protective Proteins	YES	YES
Molecular Weight	900 kDa	900 kDa
Dosing Increments	1 unit	1 unit
Diffusion*	Minimal	Minimal
Duration of Effect*	3-4 months	3-4 months
Onset of Action	72-120 hrs	72-120 hrs
Approved Indications	Glabellar Frown Lines	Glabellar Frown Lines Forehead Lines Crows Feet Migraine Headaches Excessive Sweating Muscle Spasticity
Pros/Cons	Generous Rewards Program Newest Technology – “Hi-Pure” Precise Product	Less Spread Proven Safety Resistance can develop
Tox & Tonic Membership	Available at all Tox & Tonic Locations	Available at all Tox & Tonic Locations

Manufacture Savings	Evolus	Alle’
Manufacture Savings	$40 OFF/Treatment	$20/Treatment
Enroll in Savings	Click Here	Click Here

Trade Name	JEUVEAU^®	BOTOX^®	DYSPORT^®	XEOMIN^®
Distributor	Evolus	Allergan	Galderma	Merz
Scientific Name	PrabotulinumtoxinA	OnabotulinumtoxinA	AbobotulinumtoxinA	IncobotulinumtoxinA
Year FDA Approved	2019	2002	2009	2011
Standard Price/Unit	$12/unit	$14/unit	List Price*	List Price*
Member Price	$6.99/unit	$10.50/unit	10% OFF List Price	10% OFF List Price
Protective Proteins	YES	YES	YES	NO
Molecular Weight	900 kDa	900 kDa	Varies 350-750 kDa	150 kDa
Dosing Increments	1 unit	1 unit	3 units	1 unit
Diffusion*	Minimal	Minimal	Moderate	Mild to Moderate
Duration of Effect*	3-4 months	3-4 months	3-4 months	3-4 months
Onset of Action	72-120 hrs	72 - 120 hrs	48-72 hrs	72-168 hrs
Approved Indications	Glabellar Frown Lines	Glabellar Frown Lines Forehead Lines Crows Feet Migraine Headaches Excessive Sweating Muscle Spasticity	Glabellar Frown Lines Muscle Spasticity	Glabellar Frown Lines Muscle Spasticity Excessive Drooling
Pros/Cons	Generous Rewards Program Newest Technology – “Hi-Pure” Precise Product	Less Spread Proven Safety Resistance can develop	Natural looking results Fastest Onset Avoid in Cows Milk Allergy	Longer Onset Consider use if resistance develops Lacks accessory proteins
Tox & Tonic Membership	Available at all Tox & Tonic Locations	Available at all Tox & Tonic Locations	May not be available at all Tox & Tonic Locations	May not be available at all Tox & Tonic Locations

Manufacture Savings	Evolus	Alle’	Aspire	Xperience+
Manufacturer Rewards	$40 OFF/Treatment	$20/Treatment	$20/Treatment	$20/Treatment
Enroll in Savings	Click Here	Click Here	Click Here	Click Here

*Diffusion and Duration are influenced by the amount of saline used to reconstitute each product prior to injection – this amount varies amongst providers.

*Receive per unit as part of your membership. List price is determined by individual locations.

Determining Your Treatment Areas

Not too sure what areas need to treated with Tox? Click the links below to see a quick before and after example, along with average dosing for each area.

[*Typical dose ranges shown are for Botox/Xeomin/Jeuveau – Dysport dosing is multiplied by 3]

Other Tox Treatment Options

Migraine Therapy: Typical dose 155 units.

Excessive Sweating (hyperhidrosis): Typical dose 100 units.

Sweaty Heady (for scalp sweating): Typical dose 50 units.

Micro-Tox (for skin rejuvenation): Typical Dose 60 units.

*Please note that results may vary from patient-to-patient and cannot be guaranteed. Pricing varies based upon choice of Tox and associated dosing. Not all locations carry all tox brands. Please contact your local Tox & Tonic location for more details.

All About “Tox”

What’s The Difference Between The Various ‘Tox’ Brands?

Comparison Of Currently Available “TOX” Brands

Determining Your Treatment Areas

Other Tox Treatment Options

As Seen On

Eye: Lixer Anti-Aging Eye Cream - AM/PM