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“Tox” Neuromodulators

Neuro WHAT? While the name might sound scary and, honestly, so might “tox” or “toxin”, take our word for it…. It’s NOT. Take a seat and stay for a minute, we want to give you the skinny on this unexpected nectar from the Gods. All neuromodulators are toxins and each contains the same active ingredient; a purified protein derived from Botulinum Type A that, among other things, rejuvenates facial features. When injected into facial muscles toxins temporarily block the signal to “flex” the muscle creating a smoother, more refreshed appearance. (Yes, please!) Originally, toxins were marketed for the treatment of chronic tension headaches/migraines, excessive sweating (hyperhidrosis), jaw clenching/TMJ, and other clinical conditions, but today, they are most popularly used to reduce and eliminate wrinkles. Want to learn more about how Tox can be used to improve your life?? Shoot us a message, we are always happy to chat about our most favourite subjects… TOX and TONIC!!

What about my WRINKLES!!!!???? Enough of the science lingo, let’s get straight to the point (pun intended). Tox/Neuromodulators are all used the same way… temporarily paralyzing the targeted muscle to reduce fine lines and wrinkles. Where, you ask? So many places, so little time…. Let’s run down just a few

  • On the forehead
  • Crow’s feet
  • Bunny lines
  • Chin dimpling
  • Upper lip
  • Jawline
  • Neck bands
  • Between the Brows

And SO, SO much more… also, we want to tell you a little secret (shhhh… just between us)… you don’t have to wait to get the wrinkles to treat them… (WHAT!!!????) Yes.. it’s true, we wouldn’t lie to you, we are like BFF now. So, for reals, you can treat the problem area BEFORE the wrinkle forms (seriously, it’s magical). It even has a name…it’s called “PRE-juvenation”! Even better, these are safe and simple treatments that have been around FOR-EV-ER. Using TOX is super flexible. You can start or stop whenever you want, you can even switch Tox products whenever you want (kind of reminds us of dating in college). The effects usually last about 3 months depending on your body and your metabolism, so when you start to see those pesky little lines coming back (RUDE), just pop on to the website and get your TOX ON. If you decide you like having wrinkles, (I mean, we all have our “thing”) without consistent treatment the muscle will gradually get stronger and the creases will return.

What are these “toxins” of which you speak??? The entire family of Neuromodulators (sometimes they wear matching outfits) includes Jeuveau/“NewTox”, Dysport, Xeomin, and of course Botox. Botox was the first to market and as such has become a popular household name (that is, if your household sits around the dinner table talking about neuromodulators…HUH?) anyway, the point is, sometimes you will hear “BOTOX” used in a generic way as the treatment rather than the product. But you’re so smart (I mean, you’re here aren’t you!?) you can’t be fooled that easily. You know there are other products that do the same thing (Jeuveau/“NewTox”, Dysport, Xeomin) and if you didn’t before, you do now! It is important to know that there are subtle differences in each Toxin that may play into your product choice (don’t worry, we will guide you… remember? BFFs!). To give you the “30,000 foot view” (we don’t even charge extra for that) Botox is the most costly per unit, Dysport has a quicker onset (making it very useful in wrinkle “emergencies” like… well, let’s be honest, every day is a wrinkle emergency for some of us…) Dysport pricing is listed in multiples of three because it is dosed at 3x the number of units compared to the other neuromodulators. If this all sounds very confusing, head over to our comparison chart and we will get you all sorted out!

Wow… impressive, you are still reading! This is fantastic, so let’s chat about how to figure out which product is best for YOU (cuz let’s face it, there’s nobody else like you in the entire world!!!). Because you are uniquely you, we want to see your beautiful face and make sure to customize your treatment to achieve everything you are hoping for (no, we cannot turn you into Angelina Jolie or Kim Kardashian, plus you are so much cooler and prettier than they are). Now is the time when you get crazy and try out our Virtual Consultation Tool (include link). If you aren’t into the virtual thing, we are actual humans and would love to meet you!! Go ahead and book a consultation with one of our expert injectors. When we are done perfecting the treatment you want, in the budget you want, we can hold hands and run off into the sunset. (Or, we can just make all of your wrinkles go away…totally up to you.)

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“Tox” Neuromodulators

All About “Tox”

Unless you’ve been living under a rock, by now, you’ve probably heard about Botox®. Afterall, it is that *magic* injection that improves wrinkles, skin tone, and results in HAPPINESS (it’s true….Botox® has been shown to improve depressed mood)!

While most of us refer to all “Tox” brands as “Botox” this class of medications are formally referred to as neuromodulator agents and there are several brands available for use here in the USA. Those include Jeuveau®, Dysport®, Xeomin®, and good ‘ol Botox®. In fact, all of these medications contain the same active ingredient – Botulinium Type A. Tox products work by temporarily making it harder for you to make certain facial expressions, such as frowning, thus reducing lines created by the actions of these muscles. Side effects are minimal and include the potential for bruising and mild swelling at the injection sites and treatment effects are typically seen within a few days of injection.

For more information, including a comparison chart of the various brands, click here: Membership Benefits

At Tox & Tonic we specialize in Tox injections! Our Nurse Injectors have received extensive training in the use of Tox for both on-label and off-label (commonly treated but non-FDA approved) areas with ALL of the FDA-approved Tox products currently available. We understand the differences in effect between the various brands, as well as the effect of dosing changes, precise placement, and even specialty Tox treatments such as treatments for excessive sweating, MicroTox Tightening and HydraTox Gold Needling.

Nervous about getting Tox injections?! Don’t be! Our Nurse Injectors take your safety very seriously. All potential effects – both good and bad – will be discussed with you, in detail, prior to your treatment. We will make sure you feel comfortable with your treatment plan and that all of your questions are answered. We even offer a FREE VIRTUAL CONSULTATION so you can determine which treatment areas may be right for you!

We look forward to helping you ROCK YOUR TOX!

What’s The Difference Between The Various ‘Tox’ Brands?

While the active ingredient is the same throughout all of the products, the ‘recipe’ and manufacturing process varies amongst them. This variation can create subtle differences in duration, effect, and potency as shown in the chart, below.

Please note that not all Tox brands are available at every Tox & Tonic location.

Comparison Of Currently Available “TOX” Brands

Scientific Name
Year FDA Approved
Standard Price/Unit
Member Price
Protective Proteins
Molecular Weight
900 kDa
900 kDa
Dosing Increments
1 unit
1 unit
Duration of Effect*
3-4 months
3-4 months
Onset of Action
72-120 hrs
72-120 hrs
Approved Indications
Glabellar Frown Lines
Glabellar Frown Lines Forehead Lines Crows Feet Migraine Headaches Excessive Sweating Muscle Spasticity
Generous Rewards Program Newest Technology – “Hi-Pure” Precise Product
Less Spread Proven Safety Resistance can develop
Tox & Tonic Membership
Available at all Tox & Tonic Locations
Available at all Tox & Tonic Locations
Manufacture Savings Evolus Alle’
Manufacture Savings
$40 OFF/Treatment
Enroll in Savings
Distributor Evolus Allergan Galderma Merz
Scientific Name PrabotulinumtoxinA OnabotulinumtoxinA AbobotulinumtoxinA IncobotulinumtoxinA
Year FDA Approved 2019 2002 2009 2011
Standard Price/Unit $12/unit $14/unit $12/3 units $12/unit
Member Price $6.99/unit $10.50/unit $9.99/3 units $9.99/unit
Protective Proteins YES YES YES NO
Molecular Weight 900 kDa 900 kDa Varies 350-750 kDa 150 kDa
Dosing Increments 1 unit 1 unit 3 units 1 unit
Diffusion* Minimal Minimal Moderate Mild to Moderate
Duration of Effect* 3-4 months 3-4 months 3-4 months 3-4 months
Onset of Action 72-120 hrs 72 - 120 hrs 48-72 hrs 72-168 hrs
Approved Indications Glabellar Frown Lines Glabellar Frown Lines Forehead Lines Crows Feet Migraine Headaches Excessive Sweating Muscle Spasticity Glabellar Frown Lines Muscle Spasticity Glabellar Frown Lines Muscle Spasticity Excessive Drooling
Pros/Cons Generous Rewards Program Newest Technology – “Hi-Pure” Precise Product Less Spread Proven Safety Resistance can develop Natural looking results Fastest Onset Avoid in Cows Milk Allergy Longer Onset Consider use if resistance develops Lacks accessory proteins
Tox & Tonic Membership Available at all Tox & Tonic Locations Available at all Tox & Tonic Locations May not be available at all Tox & Tonic Locations May not be available at all Tox & Tonic Locations
Manufacture Savings Evolus Alle’ Aspire Xperience+
Manufacturer Rewards $40 OFF/Treatment $20/Treatment $20/Treatment $20/Treatment
Enroll in Savings Click Here Click Here Click Here Click Here

*Diffusion and Duration are influenced by the amount of saline used to reconstitute each product prior to injection – this amount varies amongst providers.

*Receive per unit as part of your membership

Determining Your Treatment Areas

Not too sure what areas need to treated with Tox? Click the links below to see a quick before and after example, along with average dosing for each area.

[*Typical dose ranges shown are for Botox/Xeomin/Jeuveau – Dysport dosing is multiplied by 3]

Other Tox Treatment Options

Migraine Therapy: Typical dose 155 units. 

Excessive Sweating (hyperhidrosis): Typical dose 100 units. 

Sweaty Heady (for scalp sweating): Typical dose 50 units. 

Micro-Tox (for skin rejuvenation): Typical Dose 60 units.

*Please note that results may vary from patient-to-patient and cannot be guaranteed. Pricing varies based upon choice of Tox and associated dosing. Not all locations carry all tox brands. Please contact your local Tox & Tonic location for more details.

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